The Use of a Systems Approach to Increase NAD+ in Human Participants
Henderson et al.
npj Aging
Objective
Assess whether supplementation with NUCHIDO NAD+ increases NAD+ concentration in blood and whether it reduces biological age.
Methods
Thirty-three individuals were randomized to receive either NUCHIDO NAD+ supplementation or placebo for 28 days. After 28 days, the treatment and placebo groups switched for another 28 days.
Results
Participants taking NUCHIDO NAD+ supplements showed a significant increase in whole blood NAD+ concentrations, as well as an average reduction of 1.26 years in biological age compared to the placebo group.

Conclusion
Supplementation with NAD+ precursors like NUCHIDO TIME can effectively increase NAD+ concentrations in the body and contribute to a measurable reduction in biological age, suggesting its potential as a longevity-supportive intervention.

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