Publications
Peer-reviewed glycan research behind GlycanAge
GlycanAge is based on research performed on over 300,000 people. These findings
identified that glycans change 7-10 years before the disease is first diagnosed. Glycans
also respond to lifestyle interventions within a short timeframe, providing valuable
insights.
If you’re interested in including glycans in your research, check out
our GlycanAge for Research page to see how we can collaborate.
You can see all of our publications in chronological
order below.
Our research team
2026
Systemic metabolic, hormonal, and glycomic remodeling during a 72-hour fast in healthy adults: a pilot study Gordan Lauc, Petar Brlek, Luka Bulić, Nina Šimunić Briški, Jelena Šimunović, Ivana Duvnjak Orešković, Lara Butumović, Damir Marjanović, Danijela Klarić, Ana Petrović, Jan Tesla Frcko, Dragan Primorac • Croatian medical journal Physical activity and IgG N-glycosylation in medical students: a cross-sectional study Stipe Vidović, Ivanka Maduna, Matko Fančović, Nina Šimunić-Briški, Maja Hanić, Petar Šušnjara, Gordan Lauc, Marija Heffer, Lada Zibar • Croatian Medical Journal A Multi-Cohort Study of Immunoglobulin G Glycans in Newly Diagnosed Inflammatory Bowel Disease Patients Reveals Accelerated Biological Aging Konstantinos Flevaris, Irena Trbojević-Akmačić, David Goh, Juproop Singh Lalli, Frano Vučković, Marija Ćapin Vilaj, Jerko Štambuk, Jasminka Krištić, Anika Mijakovac, Nick Ventham, Rahul Kalla, Anna Latiano, Natalia Manetti, Dalin Li, Dermot PB McGovern, Nicholas A Kennedy, Vito Annese, Gordan Lauc, Jack Satsangi, Cleo Kontoravdi • medRxiv Glycan Fingerprint of Malignant Pleural Mesothelioma Lovro Kavur 1,2, Thomas S. Klari´c 3, Nikol Mraz 3, Nina Šimuni´c-Briški 3, Dora Lali´c 3, Gordan Lauc 3,4 ,Martin Martini´c 5, Lovorka Batelja Vuleti´c 6, Marina Martini´c Kavur 3,* , Sven Seiwerth 6,†and Ozren Gamulin • International Journal of Molecular Sciences (IJMS) Abstract TU188: Association of the IgG and Plasma Glycomes with Cardiometabolic Risk Factors Kiani Jacobs, Eric Leszczynski, Charles Schwartz, Michael Pitre, Prashant Rao, Michael Mi, Sujoy Ghosh, Jeremy Robbins, Robert Gerszten, Claude Bouchard, Nina Simunic-Briski, Gordan Lauc, Mark Sarzynski • Circulation Assessment of IgG N-Glycan patterns in adult patients with immune thrombocytopenia and healthy individuals Ena Ranković, Natali Nakić Bedeković, Frano Vučković, Irena Trbojević-Akmačić, Maja Pučić-Baković, Gordan Lauc, Dražen Pulanić • Glycoconj J Immunoglobulin G and plasma glycome in early rheumatoid arthritis differ from matched controls and link less fat-free mass to an accelerated aging phenotype: an exploratory study Sidra W Hashmi, Brian J Andonian, Mary M Thompson, William C Bennett, Alyssa M Sudnick, Johanna L Johnson, Leanna M Ross, Katherine A Collins-Bennett, Kelsey B Belski, Martina Vinicki, Tea Pribic, Gordan Lauc, Sridevi Krishnan, Kim M Huffman • Arthritis Research & Therapy IgG N-Glycosylation During Atorvastatin Therapy After Acute Coronary Syndrome is Associated with LDL Cholesterol Reduction Domagoj Mišković, Nikol Mraz, Barbara Radovani Trbojević, Ivana Jurin, Ana Đanić Hadžibegović, Ivan Gudelj, Gordan Lauc, Irzal Hadžibegović • MDPI Perioperative changes in IgG and plasma N-glycosylation in children with acute appendicitis and elective surgery: a prospective study Jasna Obuljen, Nikol Mraz, Tea Pribić, Irena Trbojević-Akmačić, Irena Linarić, Jasna Leniček Krleža, Stjepan Višnjić, Marko Mesić, Mislav Bastić, Anto Pajić, Neda Striber, Anđelo Beletić, Zoran Bahtijarević, Gordan Lauc, Dragan Primorac, Borna Rapčan • Croatian medical journal Association of IgG N-Glycans with Adverse Outcomes in Chronic Kidney Disease Elena Butz, Miriam IJ Bach, Fruzsina Kotsis, Inga Steinbrenner, Tamara Štambuk, Ivan Gudelj, Barbara Radovani Trbojević, Tea Pribić, Anika Mijakovac, Jennifer Nadal, Kai-Uwe Eckardt, Gordan Lauc, Anna Köttgen, Peggy Sekula, Ulla T Schultheiss, Heike Meiselbach, Markus P Schneider, Mario Schiffer, Hans-Ulrich Prokosch, Barbara Bärthlein, Andreas Beck, André Reis, Arif B Ekici, Susanne Becker, Ulrike Alberth-Schmidt, Anke Weigel, Sabine Marschall, Gerd Walz, Ulla T Schultheiß, Simone Meder, Erna Mitsch, Ursula Reinhard, Jürgen Floege, Rafael Kramann, Turgay Saritas, Elke Schaeffner, Seema Baid-Agrawal, Kerstin Theisen, Kai Schmidt-Ott, Martin Zeier, Claudia Sommerer, Gunter Wolf, Martin Busch, Thomas Sitter, Christoph Wanner, Vera Krane, Britta Bauer, Florian Kronenberg, Julia Raschenberger, Barbara Kollerits, Lukas Forer, Sebastian Schönherr, Hansi Weissensteiner, Peter Oefner, Wolfram Gronwald, Matthias Schmid • Kidney International Reports Large glycomics datasets as a tool to understand the function of glycans Maja Pučić-Baković, Tamara Štambuk, John PA Ioannidis, Vlatka Zoldoš, Wei Wang, Gordan Lauc • Nature Publishing Group US Immobilized recombinant FcγRIIIa and FcRn receptors as a tool for characterization of human IgG antibodies Lucija Dončević, Tomislav Friganović, Petra Grbčić, Marko Filipović, Iwona Borošak, Siniša Habazin, Gordan Lauc, Egbert Müller, Djuro Josić • Journal of Chromatography B Proinflammatory Epstein–Barr Virus Antibody Functions Track with Disease Activity in Multiple Sclerosis Malina Behrens, Paula Terroba‐Navajas, Eline AJ Willemse, Sabine Schädelin, Manuel Comabella, Christian Münz, Gordan Lauc, Yannic Bartsch, Jens Kuhle, Jan D Lünemann • Annals of Neurology The Immunoglobulin G Glycome: A Modifiable Biomarker and Functional Effector of Aging, Disease, and Mortality Anika Mijakovac, Elena Butz, Frano Vučković, Azra Frkatović Hodžić, Borna Rapčan, Domagoj Kifer, Helena Deriš, Barbara Radovani Trbojević, Fran Lukšić, Ana Cindrić, Ivan Gudelj, Nina Šimunić Briški, Goran Josipović, Zehra Stara Yuksel, Jasmina Ćatić, Fran Šaler, Janko Szavits-Nossan, Charlotte RH Hedin, Jelena Šimunović, Iwona Borošak, Jasminka Krištić, Sara Monteiro-Martins, Tea Pribić, Maja Hanić, Maja Pučić-Baković, Irena Trbojević-Akmačić, Tamara Štambuk, Jerko Štambuk, Marina Martinić Kavur, Matko Fančović, Ana Cvetko, Marija Pezer, Ozren Polašek, Olga Gornik, Dobri Kiprov, Eric Verdin, Brad Younggren, Louise Newson, Cristina Menni, Claire J Steves, Tim D Spector, Jonas Halfvarson, Ewa Pocheć, Marta Szewczyk, Mirjana Turkalj, James F Wilson, Marta E Alarcon-Riquelme, Konrad Aden, Philip Rosenstiel, Andre Franke, Norbert Frey, Stefan Schreiber, Ellen E Blaak, Anna Köttgen, Vlatka Zoldoš, Dragan Primorac, Damir Marjanović, Ulla T Schultheiss, Wei Wang, Gordan Lauc • medRxiv PO: 02: 044 Glycomic profiles of IgG, C3 and alpha-1-acid glycoprotein (AGP) before and one year after treatment commenced for active lupus nephritis Dionysis Nikolopoulos, Maja Pucic-Bakovic, Konstantinos Charitidis, Jelena Simunovic, Natalia Sherina, Anne-Marie Patenaude, Frano Vuckovic, Tea Pribic, Farah Tamirou, Karin Lundberg, Gordan Lauc, Frédéric A Houssiau, Ioannis Parodis • Lupus Science & Medicine Rheumatoid Arthritis-associated IgG N-glycan agalactosylation diminishes neutrophilic inflammation by reducing FcgammaR binding and downstream signaling Caroline Pumpe, Alfie Sanderson, Ballagh Forsyth, Jelena Śimunović, Yoshiki Narimatsu, Henrik Clausen, Gordan Lauc, Mark Cragg, Pierre Bruhns, Mohini Gray, Cecile Benezech, Caroline Hayward, Sonja Vermeren • bioRxiv Reconstructing N-Glycan Profiles of Individual Glycoproteins from the Total Blood Plasma N-Glycome: Implications for Immunoglobulin G N-Glycosylation GWAS Anna Soplenkova, Denis Maslov, Anna Timoshchuk, Domagoj Kifer, Ana Cvetko, Michel Georges, Claire J Steves, Cristina Menni, Sodbo Sharapov, Gordan Lauc, Yurii S Aulchenko • bioRxiv Divergent in vivo molecular responses to micro-fragmented adipose tissue and hyaluronic acid reveal disease-modifying activity of MFAT in inflammatory knee osteoarthritis Dragan Primorac, Vilim Molnar, Petar Brlek, Luka Bulić, Željko Jeleč, Uršula Prosenc Zmrzljak, Thomas Klarić, Gordan Lauc, Noël Malod-Dognin, Nataša Pržulj • medRxiv Multi-Omics Analysis of Morbid Obesity Using a Patented Unsupervised Machine Learning Platform: Genomic, Biochemical, and Glycan Insights Irena Šnajdar, Luka Bulić, Andrea Skelin, Leo Mršić, Mateo Sokač, Maja Brkljačić, Martina Matovinović, Martina Linarić, Jelena Kovačić, Petar Brlek, Gordan Lauc, Martina Smolić, Dragan Primorac • International Journal of Molecular Sciences Glycomedicine: Unveiling the paracentral dogma Wei Wang, Gordan Lauc • Elsevier Impact of Antidiabetic Medications on IgG and Plasma Protein N-Glycosylation in Type 2 Diabetes Patients Nikol Mraz, Frano Vuckovic, Tea Pribic, Anica Rados Kajic, Tomas Matic, Edita Pape Medvidovic, Vilma Kolaric, Dario Rahelic, Gordan Lauc, Tamara Stambuk • medRxiv
2025
Quantitative Modeling of IgG N-Glycosylation Profiles from Population Data Elena Kutumova, Nikita Mandrik, Ruslan Sharipov, Maja Pučić-Baković, Borna Rapčan, Yurii Aulchenko, Gordan Lauc, Fedor Kolpakov • International Journal of Molecular Sciences Phosphorylation of N-glycans in the brain: The case for a non-canonical pathway? Lucija Sironić, Nikol Mraz, Gordan Lauc, Thomas S Klarić • BBA advances Total cell N-glycosylation is altered during differentiation of induced pluripotent stem cells to neural stem cells and is disturbed by trisomy 21 Ana Cindrić, Frano Vučković, Aoife Murray, Thomas S Klarić, Ivan Alić, Jasminka Krištić, Dean Nižetić, Gordan Lauc • BBA advances METHOD FOR PREDICTION OF FUTURE CARDIOVASCULAR DISEASE RISK VIA ANALYSIS OF IgG GLYCOME Branimir PLAVSA, Gordan Lauc, Samia Mora, Rosangela AKEMI HOSHI, Olga DEMLER • US Patent App. 18/231,793 Statin effects on immunoglobulin-G glycomic architecture and the link to cardiovascular disease Azam Yazdani, Rosangela Hoshi, Mohammed Ammar, Chunying Li, Richard D Cummings, Irena Akmačić-Trbojević, Ana Cindrić, Nina Šimunić-Briški, Ivan Gudelj, Robert Glynn, Paul Ridker, Daniel I Chasman, Gordan Lauc, Olga Demler, Samia Mora • Research Square Effects of testosterone and metformin on the GlycanAge index of biological age and the composition of the IgG glycome Martina Vinicki, Tea Pribić, Frano Vučković, Azra Frkatović-Hodžić, Isaac Plaza-Andrades, Francisco Tinahones, Joseph Raffaele, José Carlos Fernández-García, Gordan Lauc • Geroscience Invigorating discovery and clinical translation of aging biomarkers Erik Jacques, Chiara Herzog, Kejun Ying, Alan Tomusiak, Jessica Kasamoto, Raghav Sehgal, Seth Paulson, Julian Reinhard, Jakob Träuble, Waylon J Hastings, Alexander Tyshkovskiy, Sara Hägg, John C Earls, Christian E Behrens, Jessica Lasky-Su, Gavin Zhou, Eric Morgen, John S Tsang, Riccardo E Marioni, Xiao-Jun Ma, Alexandra Stolzing, Christin Glorioso, Jonathan S Gootenberg, Omar O Abudayyeh, M Austin Argentieri, Raymond H Mak, Lynne S Cox, Andrew S Brack, Gordan Lauc, David Furman, Jason D Buenrostro, Björn Schumacher, Jamie N Justice, Tina Woods, David Gobel, Viviana I Perez, David A Sinclair, Andrea B Maier, Nir Barzilai, Michael P Snyder, Tony Wyss-Coray, Steve Horvath, Luigi Ferrucci, Jesse R Poganik, Mahdi Moqri, Vadim N Gladyshev • Nature Aging A plasma glycan score for cardiovascular risk prediction: Secondary analysis of the JUPITER and TNT studies Mohammed Ammar, Azam Yazadani, Rosangela Hoshi, Irena Trbojevic-Akmacic, Robert Glynn, Paul Ridker, Richard Cummings, Gordan Lauc, Olga Demler, Samia Mora • Journal of Clinical Lipidology POS1203 GLYCOSYLATION CHANGES OF IgG, C3 AND ALPHA-1-ACID GLYCOPROTEIN (AGP) OVER ONE YEAR OF TREATMENT FOR INCIDENT LUPUS NEPHRITIS ARE ASSOCIATED WITH RENAL OUTCOME D Nikolopoulos, M Pučić-Baković, J Šimunović, AM Patenaude, F Vučković, T Pribić, F Tamirou, G Lauc, F Houssiau, Ioannis Parodis • Annals of the Rheumatic Diseases A genome-wide association study in 10,000 individuals links plasma N-glycome to liver disease and anti-inflammatory proteins Sodbo Sharapov, Anna Timoshchuk, Olga Zaytseva, Denis E Maslov, Anna Soplenkova, Elizaveta E Elgaeva, Evgeny S Tiys, Massimo Mangino, Clemens Wittenbecher, Lennart Karssen, Maria Timofeeva, Arina Nostaeva, Frano Vuckovic, Irena Trbojević-Akmačić, Tamara Štambuk, Sofya Feoktistova, Nadezhda A Potapova, Viktoria Voroshilova, Frances Williams, Dragan Primorac, Jan Van Zundert, Michel Georges, Karsten Suhre, Massimo Allegri, Nishi Chaturvedi, Malcolm Dunlop, Matthias B Schulze, Tim Spector, Yakov A Tsepilov, Gordan Lauc, Yurii S Aulchenko • Nature communications Contrasting macroevolutionary patterns in the human N-glycosylation pathway Domagoj Kifer, Nina Čorak, Mirjana Domazet-Lošo, Niko Kasalo, Gordan Lauc, Göran Klobučar, Tomislav Domazet-Lošo • Engineering A 2-year calorie restriction intervention may reduce glycomic biological age biomarkers–a pilot study Tea Pribić, Jayanta K Das, Lovorka Đerek, Daniel W Belsky, Melissa Orenduff, Kim M Huffman, William E Kraus, Helena Deriš, Jelena Šimunović, Tamara Štambuk, Azra Frkatović-Hodžić, Virginia B Kraus, Sai Krupa Das, Susan B Racette, Nirad Banskota, Luigi Ferrucci, Carl Pieper, Nathan E Lewis, Gordan Lauc, Sridevi Krishnan • npj Aging Longitudinal study reveals plasma glycans associations with prediabetes/type 2 diabetes in KORA study Jiefei Niu, Elke Rodriguez, Tamara Štambuk, Irena Trbojević-Akmačić, Nikol Mraz, Jochen Seissler, Thomas Skurk, Sabrina Schlesinger, Annette Peters, Gordan Lauc, Christian Gieger, Harald Grallert • Cardiovascular Diabetology Longitudinal study reveals plasma glycans associations with prediabetes/type 2 diabetes in KORA F4/FF4 J Niu, A Peters, G Lauc, C Gieger, H Grallert • DIABETOLOGIA Combining blood biochemistry and glycan ages for an even more prognostic biological age Azra Frkatović-Hodžić, Jordan Bortz, Andrea Guarglia, Erin Macdonald Dunlop, Anika Mijakovac, Nina Šimunić Briški, Peter Ward, Ozren Polašek, Gordan Lauc, Michael Geer, James F Wilson, Peter K Joshi • medRxiv Immune and inflammatory resolution pathways through multi-omics using the AI-based Network Integration Azam Yazdani, Anika Mijakovac, Franco Giulianini, Mona Alotaibi, Heike Gibson, Mohammed Ammar, Rosangela Hoshi, Richard D Cummings, Charles N Serhan, Gordan Lauc, Daniel Chasman, Samia Mora • Research Square # 2033 First small steps… a pilot study on changes in Immunoglobulin G N-glycome during immunosuppressive treatment of ANCA-associated vasculitis Matija Crnogorac, Anđelo Beletić, Lovorka Djerek, Ana Strizić, Maja Hanić, Ivica Horvatić, Gordan Lauc • Nephrology Dialysis Transplantation Immunoglobulin G N-glycosylation as a novel biomarker for premature myocardial infarction: a case-control study M Ammar, S Dugani, H Gibson, MV Moorthy, J Atos, Y Hydoub, O Demler, G Lauc, A Alsheikh-Ali, S Mora • European Heart Journal Plasma Protein N-Glycosylation Profiles Are Associated with Future Cardiovascular Events: Analyses from the JUPITER and TNT Trials Mohammed Ammar, Rosangela Hoshi, Azam Yazdani, Irena Trbojevic-Akmacic, Robert Glynn, Franco Giulianini, Paul Ridker, Richard Cummings, Gordan Lauc, Olga Demler, Samia Mora • Circulation Therapy-induced remodeling of IgG and plasma N-glycans in breast cancer Martina Maričić Vrban, Barbara Radovani Trbojević, David Visentin, Katarina Ramljak, Iva Kirac, Mihaela Gaće, Ivan Milas, Gordan Lauc, Dragan Primorac, Ivan Gudelj • BMC cancer Exploration of Augmentation Strategies in Multi-modal Retrieval-Augmented Generation for the Biomedical Domain: A Case Study Evaluating Question Answering in Glycobiology Primož Kocbek, Azra Frkatović-Hodžić, Dora Lalić, Vivian Hui, Gordan Lauc, Gregor Štiglic • arXiv preprint arXiv:2512.16802
2024
STATINS’EFFECT ON IMMUNOGLOBULIN-G-GLYCOMIC ARCHITECTURE AND THE LINK TO CVD Azam Yazdani, Rosangela Hoshi, Mohammed Ammar, Chunying Li, Richard Cummings, Ivan Gudelj, Paul Ridker, Robert Glynn, Gordan Lauc, Daniel Chasman, Olga Demler, Samia Mora • Atherosclerosis A unique serum IgG glycosylation signature predicts development of Crohn’s disease and is associated with pathogenic antibodies to mannose glycan Joana Gaifem, Cláudia S Rodrigues, Francesca Petralia, Inês Alves, Eduarda Leite-Gomes, Bruno Cavadas, Ana M Dias, Catarina Moreira-Barbosa, Joana Revés, Renee M Laird, Mislav Novokmet, Jerko Štambuk, Siniša Habazin, Berk Turhan, Zeynep H Gümüş, Ryan Ungaro, Joana Torres, Gordan Lauc, Jean-Frederic Colombel, Chad K Porter, Salomé S Pinho • Nature Immunology Predicting biochemical and physiological parameters: deep learning from IgG glycome composition Ana Vujić, Marija Klasić, Gordan Lauc, Ozren Polašek, Vlatka Zoldoš, Aleksandar Vojta • International journal of molecular sciences GlyCoDA: A compositional data analysis and domain adaptation perspective on disease risk prediction using plasma IgG N-glycans Konstantinos Flevaris, Irena Trbojević-Akmačić, Gordan Lauc, Cleo Kontoravdi • Welcome Letter Glycan clock of ageing—analytical precision and time-dependent inter-and i-individual variability Borna Rapčan, Manshu Song, Azra Frkatović-Hodžić, Tea Pribić, Jakov Vuk, Anđelo Beletić, Maja Hanić, Julija Jurić, Petra Tominac, Josip Milas, Vedrana Ivić, Sven Viland, Sara Bonet, Branko Šego, Marija Heffer, Wei Wang, Michael P Snyder, Gordan Lauc • GeroScience N-GLYCOSYLATION PROFILES OF PLASMA GLYCANS AND FUTURE CARDIOVASCULAR EVENTS Mohammed Ammar, Rosangela Hoshi, Azam Yazdani, Matea Mihelcic, Irena Trbojevic-Akmacic, Robert Glynn, Paul Ridker, Richard Cummings, Gordan Lauc, Olga Demler, Samia Mora • Atherosclerosis Genetic control of population diversity in human immunoglobulin G N-glycosylation Anna Soplenkova, Denis Maslov, Anna Timoshchuk, Tim Spector, Michel Georges, Sodbo Sharapov, Gordan Lauc, Yury Aulchenko • EUROPEAN JOURNAL OF HUMAN GENETICS A genome-wide association study of the plasma N-glycome of 10,000 individuals significantly expands the list of associated loci Sodbo Sharapov, Anna Timoshchuk, Olga Zaytseva, Denis Maslov, Anna Soplenkova, Elizaveta Elgaeva, Frano Vuckovic, Irena Trbojevic-Akmacic, Frances Williams, Dragan Primorac, Jan Van Zundert, Michel Georges, Karsten Suhre, Massimo Allegri, Nish Chaturvedi, Malcolm Dunlop, Matthias Bernd Schulze, Tim Spector, Yakov Tsepilov, Gordan Lauc, Yury Aulchenko • EUROPEAN JOURNAL OF HUMAN GENETICS Alterations in serum IgG glycome are associated with Crohn's disease development Joana Gaifem, Claudia Rodrigues, Francesca Petralia, Ines Alves, Eduarda Leite-Gomes, Bruno Cavadas, Ana M Dias, Catarina Moreira-Barbosa, Joana Reves, Renee M Laird, Mislav Novokmet, Jerko Stambuk, Sinisa Habazin, Berk Turhan, Zeynep H Gumus, Ryan Ungaro, Joana Torres, Gordan Lauc, Jean-Frederic Colombel, Chad K Porter, Salome S Pinho • EUROPEAN JOURNAL OF IMMUNOLOGY Variability of human Alpha-1-acid glycoprotein N-glycome in a Caucasian population Frano Vučković, Mislav Novokmet,Frano Vučković, Gordan Lauc, at al. • GLYCOBIOLOGY N-Glycosylation Profiles of Immunoglobulin G and Future Cardiovascular Events Hoshi RA, et al. • Circulation Research Functional Signature of LRP4 Antibodies in Myasthenia Gravis Omar Chuquisana, at al. • Neurology Journals Influence of Desialylation on the Drug Binding Affinity of Human Alpha-1-Acid Glycoprotein Assessed by Microscale Thermophoresis Šeba T, et al. • Pharmaceutics The use of a systems approach to increase NAD+ in human participants Henderson JD, et al. • npj Aging MMP3 single-nucleotide polymorphisms are associated with noncontact ACL injuries in competing high-level athletes Šimunić-Briški N, et al. • Journal of Orthopaedic Research Anastrozole and Tamoxifen Impact on IgG Glycome Composition Dynamics in Luminal A and Luminal B Breast Cancers Rapčan B, et al. • Antibodies Alterations in plasma protein N-glycosylation after caloric restriction and bariatric surgery Štambuk T, et al. • Surgery for Obesity and Related Diseases
2023
Plasma protein N-glycome composition associates with postprandial lipaemic response Louca P, et al. • BMC Medicine Total serum N-glycans associate with response to immune checkpoint inhibition therapy and survival in patients with advanced melanoma Visconti A, et al. • BMC Cancer Dose imbalance of DYRK1A kinase causes systemic progeroid status in Down syndrome by increasing the un-repaired DNA damage and reducing LaminB1 levels Murray A, et al. • eBioMedicine Human complement component C3 N-glycome changes in type 1 diabetes complications Šoić D, et al. • Frontiers in Endocrinology IgG N-glycans are associated with prevalent and incident complications of type 2 diabetes Memarian E, et al. • Diabetes/Metabolism Research and Reviews Comparative analysis of transferrin and IgG N-glycosylation in two human populations Trbojević-Akmačić I, et al. • Communications Biology High-throughput immunoaffinity enrichment and N-glycan analysis of human plasma haptoglobin Šimunović J., et al. • Biotechnology and Bioengineering Storage stability and HILIC-UHPLC-FLR analysis of immunoglobulin G N-glycome from saliva Radovani B, et al. • Analytical and Bioanalytical Chemistry The Association of the Polymorphisms in the FUT8-Related Locus with the Plasma Glycosylation in Post-Traumatic Stress Disorder Tudor L, et al. • International Journal of Molecular Sciences Periodic Changes in the N-Glycosylation of Immunoglobulin G During the Menstrual Cycle Jurić J, et al. • Engineering Higher MRI lesion load in multiple sclerosis is related to the N-glycosylation changes of cerebrospinal fluid immunoglobulin G Turčić A, et al. • Multiple Sclerosis and Related Disorders Anti-TNF Biologicals Enhance the Anti-Inflammatory Properties of IgG N-Glycome in Crohn's Disease Hanić M, et al. • Biomolecules The N-Glycosylation of Total Plasma Proteins and IgG in Atrial Fibrillation Branimir Plavša B, et al. • Biomolecules IgG N-Glycosylation Is Altered in Coronary Artery Disease Radovani B, et al. • Biomolecules Mapping of the gene network that regulates glycan clock of ageing Azra Frkatović-Hodžić A, et al. • Aging Regular moderate physical exercise decreases Glycan Age index of biological age and reduces inflammatory potential of Immunoglobulin G Šimunić-Briški N, et al. • Glycoconjugate Journal Can we suppress chronic systemic inflammation and postpone age-related diseases by targeting the IgG glycome? Lauc G, et al. • Expert Opinion on Therapeutic Targets Reversal of Biological Age in Multiple Rat Organs by Young Porcine Plasma Fraction Horvath S, et al. • Geroscience IgG glycans in health and disease: Prediction, intervention, prognosis, and therapy Shkunnikova S, et al. • Biotechnology Advances Not-So-Sweet Dreams: Plasma and IgG N-Glycome in the Severe Form of the Obstructive Sleep Apnea Doris Plećaš et al. • Biomolecules IgG glycans in health and disease: Prediction, intervention, prognosis, and therapy Sofia Shkunnikova et al. • ScienceDirect Human-specific features and developmental dynamics of the brain N-glycome Thomas S Klarić et al. • NCBI PubMed
2022
Blood plasma/IgG N-glycome biosignatures associated with major depressive disorder symptom severity and the antidepressant response Gordan Lauc et al. • Nature Immunoglobulin G N-Glycosylation Signatures in Incident Type 2 Diabetes and Cardiovascular Disease Gordan Lauc et al. • Diabetes Journals Glycosylation Profile of Immunoglobulin G and Incident Cardiovascular Events: Secondary Analysis of Two Randomized Clinical Trials Gordan Lauc et al. • AHA Journals Heritability of the glycan clock of biological age Anika Mijakovac et al. • Frontiers Differences in Immunoglobulin G Glycosylation Between Influenza and COVID-19 Patients Marina Kljaković-Gašpić Batinjan et al. • Sience Direct Effects of low-calorie and different weight-maintenance diets on IgG glycome composition Helena Deriš et al. • Frontiers A catalogue of omics biological ageing clocks reveals substantial commonality and associations with disease risk Azra Frkatović et al. • Aging High-throughput human complement C3 N-glycoprofiling identifies markers of early onset type 1 diabetes mellitus in children Dinko Šoić et al • MCP Immunoglobulin G glycans – Biomarkers and molecular effectors of aging Jasminka Krištić et al • ScienceDirect Baseline IgG-Fc N-glycosylation profile is associated with long-term outcome in a cohort of early inflammatory arthritis patients Sénard et al • BMC Arthritis Research & Therapy Distinct Longitudinal Changes in Immunoglobulin G N-Glycosylation Associate with Therapy Response in Chronic Inflammatory Diseases Jerko Štambuk et al • MDPI, International Journal of Molecular Sciences The dynamic brain N-glycome Thomas S. Klarić & Gordan Lauc • Springer Fucosylated AGP glycopeptides as biomarkers of HNF1A-Maturity onset diabetes of the young Marko Tijardovic et al. • Elsevier A Transient Expression System with Stably Integrated CRISPR-dCas9 Fusions for Regulation of Genes Involved in Immunoglobulin G Glycosylation Gordan Lauc, et al. • The CRISPR Journal Immunoglobulin G glycome composition in transition from premenopause to postmenopause Gordan Lauc et al. • iScience Altered IgG glycosylation at COVID-19 diagnosis predicts disease severity Gordan Lauc, et al. • European Journal of Immunology Developments and perspectives in high-throughput protein glycomics: enabling the analysis of thousands of samples Gordan Lauc, PhD et al. • Oxford Academic N-Glycosylation and Inflammation; the Not-So-Sweet Relation Ivan Gudelj and Barbara Radovani • Frontiers High-Throughput Glycomic Methods Gordan Lauc et al. • Chemical Reviews IgG N-glycome changes during the course of severe COVID-19: An observational study Tea Petrović, et al. • The Lancet
2021
N-glycosylation of immunoglobulin G predicts incident hypertension Gordan Lauc et al. • Journal of hypertension Plasma N-glycome shows continuous deterioration as the diagnosis of insulin resistance approaches Ana Cvetko, et al. • BMJ Journals A Multi-Factorial Observational Study on Sequential Fecal Microbiota Transplant in Patients with Medically Refractory Clostridioides difficile Infection Tanya M. Monaghan, et al. • Cells Investigation of the causal relationships between human IgG N-glycosylation and twelve common diseases associated with changes in the IgG N-glycome Olga O Zaytseva, et al. • Oxford Academic Immunoglobulin G glycome composition in transition from pre-menopause to menopause Domagoj Kifer, et al. • MedRxiv Targeting B cells in the pre-phase of systemic autoimmunity globally interferes with autoimmune pathology Anja Werner, et al. • Cell Effects of Estradiol on Immunoglobulin G Glycosylation: Mapping of the Downstream Signaling Mechanism Anika Mijakovac, et al. • Frontiers in Immunology Multiomics Profiling Reveals Signatures of Dysmetabolism in Urban Populations in Central India Tanya M. Monaghan, et al. • Microorganisms Systems Glycobiology: Immunoglobulin G Glycans as Biomarkers and Functional Effectors in Aging and Diseases Marija Martinić Kavur, Gordan Lauc and Marija Pezer • ScienceDirect Extensive weight loss reduces glycan age by altering IgG N-glycosylation Valentina L Greto, et al. • International Journal of Obesity
2020
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