Mind Full of Glycans
We truly have a treat for you - a lecture taught by Thomas Klarić, a member of our team researching the human glycome project. The lecture is titled The Mind Full of Glycans - an insight into the importance of glycans for the neurobiological processes in our brain.
We truly have a treat for you - a lecture taught by Thomas Klarić, a member of our team researching the human glycome project. The lecture is titled The Mind Full of Glycans - an insight into the importance of glycans for the neurobiological processes in our brain.
Glycosylation plays a crucial role in the development and normal functioning of the central nervous system. The latest research indicates that the glyco-profile of the brain is dynamic and can be modified in response to intrinsic and extrinsic factors.
In this lecture, we will examine some of the factors that can affect the glycosylation of brain proteins with a special focus on ageing and inflammation. In addition, we will also explore the link between changes in Immunoglobulin G glycosylation and various neurological disorders.
We’ll start by explaining the difference between GlycanAge and Brain N-glycome as well as why we use one instead of the other when researching neurological disorders. After that, we’ll go into human brain development and specific ailments like brain cancer, MS and PTSD.
Glycan science and biological age
Go deeper with GlycanAge for research and cohort studies, peer-reviewed GlycanAge research case studies, and methodology behind glycan-based biological age testing.
The Future of Healthcare is Preventative, Personalised, and Powered by Glycans
Whether you’re improving your own health, supporting patients, or driving research, GlycanAge helps you turn science into action.
O-linked Glycosylation Explained
The blueprint for how proteins are formed is encoded in our DNA, but that’s only part of the story. Once a protein is built, it can undergo further modifications through the attachment of various molecules, altering its structure and function. These changes, collectively known as post-translational modifications, play…
Published:August 27, 2024
Reading time:10 minutes
Glycosylation: Impact on Health and Disease
Glycans are essential for all life. These are long-chain sugars that are present on proteins, lipids (also known as fats) and nucleic acids, and which make these biomolecules functional. When we think of sugars, our first thought may be about the sugars from food we eat, such as glucose and sucrose.
Published:April 29, 2024
Reading time:15 minutes