IgG glycans in health and disease: Prediction, intervention, prognosis, and therapy
Sofia Shkunnikova et al. - ScienceDirect
https://www.sciencedirect.com/science/article/pii/S0734975023000769GlycanAge publications
GlycanAge is based on research performed on over 200,000 people.
These findings identified that glycans change 7-10 years before the disease is first diagnosed. Glycans also respond to lifestyle interventions within a short timeframe, providing valuable insights.
If you’re interested in including glycans in your research, check out our Research page to see how we can collaborate.
You can see all of our publications in chronological order below.
2023
Not-So-Sweet Dreams: Plasma and IgG N-Glycome in the Severe Form of the Obstructive Sleep Apnea
Doris Plećaš et al. - Biomolecules
https://www.mdpi.com/2218-273X/13/6/880Human-specific features and developmental dynamics of the brain N-glycome
Thomas S Klarić et al. - NCBI PubMed
https://pubmed.ncbi.nlm.nih.gov/36711977/2022
Immunoglobulin G N-Glycosylation Signatures in Incident Type 2 Diabetes and Cardiovascular Disease
Gordan Lauc et al. - Diabetes Journals
https://diabetesjournals.org/care/article/45/11/2729/147697/Immunoglobulin-G-N-Glycosylation-Signatures-inThe dynamic brain N-glycome
Thomas S. Klarić & Gordan Lauc - Springer
https://link.springer.com/article/10.1007/s10719-022-10055-xHigh-throughput human complement C3 N-glycoprofiling identifies markers of early onset type 1 diabetes mellitus in children
Dinko Šoić et al - MCP
https://www.mcponline.org/article/S1535-9476(22)00215-8/fulltextDistinct Longitudinal Changes in Immunoglobulin G N-Glycosylation Associate with Therapy Response in Chronic Inflammatory Diseases
Jerko Štambuk et al - MDPI, International Journal of Molecular Sciences
https://www.mdpi.com/1422-0067/23/15/8473Glycosylation Profile of Immunoglobulin G and Incident Cardiovascular Events: Secondary Analysis of Two Randomized Clinical Trials
Gordan Lauc et al. - AHA Journals
https://www.ahajournals.org/doi/abs/10.1161/circ.146.suppl_1.11057Blood plasma/IgG N-glycome biosignatures associated with major depressive disorder symptom severity and the antidepressant response
Gordan Lauc et al. - Nature
https://www.nature.com/articles/s41598-017-17500-0N-Glycosylation and Inflammation; the Not-So-Sweet Relation
Ivan Gudelj and Barbara Radovani - Frontiers
https://www.frontiersin.org/articles/10.3389/fimmu.2022.893365/fullDevelopments and perspectives in high-throughput protein glycomics: enabling the analysis of thousands of samples
Gordan Lauc, PhD et al. - Oxford Academic
https://academic.oup.com/glycob/article/32/8/651/6572164Immunoglobulin G glycome composition in transition from premenopause to postmenopause
Gordan Lauc et al. - iScience
https://www.cell.com/iscience/pdf/S2589-0042(22)00167-5.pdf?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2589004222001675%3Fshowall%3DtrueEffects of low-calorie and different weight-maintenance diets on IgG glycome composition
Helena Deriš et al. - Frontiers
https://www.frontiersin.org/articles/10.3389/fimmu.2022.995186/abstractImmunoglobulin G glycans – Biomarkers and molecular effectors of aging
Jasminka Krištić et al - ScienceDirect
https://www.sciencedirect.com/science/article/abs/pii/S0009898122012578High-Throughput Glycomic Methods
Gordan Lauc et al. - Chemical Reviews
https://pubs.acs.org/doi/10.1021/acs.chemrev.1c01031Heritability of the glycan clock of biological age
Anika Mijakovac et al. - Frontiers
https://www.frontiersin.org/articles/10.3389/fcell.2022.982609/abstractFucosylated AGP glycopeptides as biomarkers of HNF1A-Maturity onset diabetes of the young
Marko Tijardovic et al. - Elsevier
https://www.diabetesresearchclinicalpractice.com/action/showPdf?pii=S0168-8227%2822%2900038-9Baseline IgG-Fc N-glycosylation profile is associated with long-term outcome in a cohort of early inflammatory arthritis patients
Sénard et al - BMC Arthritis Research & Therapy
https://arthritis-research.biomedcentral.com/articles/10.1186/s13075-022-02897-5Altered IgG glycosylation at COVID-19 diagnosis predicts disease severity
Gordan Lauc, et al. - European Journal of Immunology
https://onlinelibrary.wiley.com/doi/10.1002/eji.202149491IgG N-glycome changes during the course of severe COVID-19: An observational study
Tea Petrović, et al. - The Lancet
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(22)00282-1/fulltextA Transient Expression System with Stably Integrated CRISPR-dCas9 Fusions for Regulation of Genes Involved in Immunoglobulin G Glycosylation
Gordan Lauc, et al. - The CRISPR Journal
https://www.liebertpub.com/doi/epub/10.1089/crispr.2021.0089A catalogue of omics biological ageing clocks reveals substantial commonality and associations with disease risk
Azra Frkatović et al. - Aging
https://www.aging-us.com/article/203847/textDifferences in Immunoglobulin G Glycosylation Between Influenza and COVID-19 Patients
Marina Kljaković-Gašpić Batinjan et al. - Sience Direct
https://www.sciencedirect.com/science/article/pii/S20958099220063122021
Multiomics Profiling Reveals Signatures of Dysmetabolism in Urban Populations in Central India
Tanya M. Monaghan, et al. - Microorganisms
https://www.mdpi.com/2076-2607/9/7/1485Investigation of the causal relationships between human IgG N-glycosylation and twelve common diseases associated with changes in the IgG N-glycome
Olga O Zaytseva, et al. - Oxford Academic
https://academic.oup.com/hmg/advance-article-abstract/doi/10.1093/hmg/ddab335/6428118?fbclid=IwAR3-VPO6KBeiEcIedUDJXtyLBDezfo7jwL7HM2APOtMj9izx901YOhM6p1YEffects of Estradiol on Immunoglobulin G Glycosylation: Mapping of the Downstream Signaling Mechanism
Anika Mijakovac, et al. - Frontiers in Immunology
https://www.frontiersin.org/articles/10.3389/fimmu.2021.680227/fullTargeting B cells in the pre-phase of systemic autoimmunity globally interferes with autoimmune pathology
Anja Werner, et al. - Cell
https://www.cell.com/iscience/fulltext/S2589-0042(21)01044-0#%20Plasma N-glycome shows continuous deterioration as the diagnosis of insulin resistance approaches
Ana Cvetko, et al. - BMJ Journals
https://drc.bmj.com/content/9/1/e002263.infoExtensive weight loss reduces glycan age by altering IgG N-glycosylation
Valentina L Greto, et al. - International Journal of Obesity
https://www.nature.com/articles/s41366-021-00816-3.epdf?sharing_token=NHFBegLn0sO-YJ-1a9x3ttRgN0jAjWel9jnR3ZoTv0NODh881xrqt-RyR9vH4f4bcJyK9xkbke9NyB5E97YF7AcOicx1_8mlvl97vmAu1cJg_-uBLa2_pkSubBtpRYfJ_VNwpMWjRkWlZmYwzp7D7sSLfUchh_094Ch8ip26tiY%3DA Multi-Factorial Observational Study on Sequential Fecal Microbiota Transplant in Patients with Medically Refractory Clostridioides difficile Infection
Tanya M. Monaghan, et al. - Cells
https://www.mdpi.com/2073-4409/10/11/3234Systems Glycobiology: Immunoglobulin G Glycans as Biomarkers and Functional Effectors in Aging and Diseases
Marija Martinić Kavur, Gordan Lauc and Marija Pezer - ScienceDirect
https://firebasestorage.googleapis.com/v0/b/genos-glyco.appspot.com/o/Systems%20Glycobiology.pdf?alt=media&token=c29421fa-d9fc-40f4-a34c-b15cb6ab9d0bN-glycosylation of immunoglobulin G predicts incident hypertension
Gordan Lauc et al. - Journal of hypertension
https://journals.lww.com/jhypertension/Fulltext/2021/12000/N_glycosylation_of_immunoglobulin_G_predicts.24.aspxImmunoglobulin G glycome composition in transition from pre-menopause to menopause
Domagoj Kifer, et al. - MedRxiv
https://www.medrxiv.org/content/10.1101/2021.04.10.21255252v12020
Composition of the immunoglobulin G glycome associates with the severity of COVID-19
Tea Petrović, et al. - Glycobiology
https://academic.oup.com/glycob/advance-article/doi/10.1093/glycob/cwaa102/5970509N-glycans as functional effectors of genetic and epigenetic disease risk
Tamara Štambuk et al. - Science direct
https://www.sciencedirect.com/science/article/abs/pii/S009829972030056X?via%3DihubDecreased Immunoglobulin G Core Fucosylation, A Player in Antibody-dependent Cell-mediated Cytotoxicity, is Associated with Autoimmune Thyroid Diseases
Tiphaine C. Martin, et al. - Mollecular & Cellular proteomics
https://www.mcponline.org/article/S1535-9476(20)35003-9/fulltextMinimal B Cell Extrinsic IgG Glycan Modifications of Pro- and Anti-Inflammatory IgG Preparations in vivo
Anja Schaffert, et al. - Frontiers in Immunology
https://www.frontiersin.org/articles/10.3389/fimmu.2019.03024/fullGlycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases
Lucija Klarić, et al. - Science Advances
https://advances.sciencemag.org/content/6/8/eaax0301Searching for glycomic biomarkers for predicting resilience and vulnerability in a rat model of posttraumatic stress disorder
Csilla Lea Fazekasab, et al. - The International Journal on the Biology of Stress
https://www.tandfonline.com/doi/abs/10.1080/10253890.2020.1795121?journalCode=ists20Effects of estradiol on biological age measured using the glycan age index
Julija Jurić, et al. - Ageing
https://www.aging-us.com/article/104060Biomarkers of biological age as predictors of COVID-19 disease severity
Gordan Lauc, David Sinclair - Ageing
https://www.aging-us.com/article/103052Plasma n-glycans as emerging biomarkers of cardiomatabolic risk: a prospective investigation in the epic-potsdam cohort study
C Wittenbecher, et al. - Diabetes Care
https://care.diabetesjournals.org/content/early/2020/01/06/dc19-1507Global variability of the human IgG glycome
Jerko Štambuk, et al. - Ageing
https://www.aging-us.com/article/103884/text2019
IgG Glycans as a Biomarker of Biological Age
M. Vilaj et al. - Springer
https://link.springer.com/chapter/10.1007/978-3-030-24970-0_7Decreased Complexity of Serum N-glycan Structures Associates with Successful Fecal Microbiota Transplantation for Recurrent Clostridioides difficile Infection
Tanya M. Monaghan et al. - Gastroenterology
https://www.gastrojournal.org/article/S0016-5085(19)41259-6/fulltext?referrer=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2FGlycomics for type 2 diabetes biomarker discovery: promise of immunoglobulin g subclass-specific fragment crystallizable n-glycosylation in the Uyghur population.
Liu J, et al. - Omics: a Journal of Integrative Biology
https://www.ncbi.nlm.nih.gov/pubmed/31393219N-glycan analysis by ultra-performance liquid chromatography and capillary gel electrophoresis with fluorescent labelling.
Hanic M, et al. - Current protocols in protein science
https://www.ncbi.nlm.nih.gov/pubmed/31517449Supplementation with the sialic acid precursor n-acetyl-d-mannosamine breaks the link between obesity and hypertension.
Jun Peng, et al. - Circulation
https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.119.043490Association of the IgG N-glycome with the course of kidney function in type 2 diabetes
Sunny S Singh, et al. - BMJ Journals
https://drc.bmj.com/content/8/1/e001026.longInflammatory bowel disease - glycomics perspective.
Wang H, et al. - Biochimica et Biophysica Acta
https://www.ncbi.nlm.nih.gov/pubmed/31276732Translational glycobiology: from bench to bedside.
Axford J, et al. - Journal of Royal Society of Medicine
https://www.ncbi.nlm.nih.gov/pubmed/31526214Comprehensive n-glycosylation analysis of immunoglobulin g from dried blood spots
Simunovic J, et al. - Glycobiology
https://www.ncbi.nlm.nih.gov/pubmed/31410450Molecular pathways mediating immunosuppression in response to prolonged intensive physical training, low-energy availability, and intensive weight loss.
Sarin HV, et al. - Frontiers in Immunology
https://www.ncbi.nlm.nih.gov/pubmed/31134054Altered n-glycosylation profiles as potential biomarkers and drug targets in diabetes.
Rudman N, et al. - FEBS Letters
https://www.ncbi.nlm.nih.gov/pubmed/31215021Type 2 diabetes mellitus is associated with the immunoglobulin g n-glycome through putative proinflammatory mechanisms in an Australian population.
Li X, et al. - Omics: a Journal of Integrative Biology
https://www.ncbi.nlm.nih.gov/pubmed/31526239Intense physical exercise indicates an anti-inflammatory change in igg n-glycosylation profile
Marko Tijardović, et al. - Frontiers in Physiology
https://www.frontiersin.org/articles/10.3389/fphys.2019.01522/fullNext-generation (glycomic) biomarkers for cardiometabolic health: a community-based study of immunoglobulin g n-glycans in a Chinese Han population.
Wang H, et al. - Omics: a Journal of Integrative Biology
https://www.ncbi.nlm.nih.gov/pubmed/31313980Breaking the glyco-code of HIV persistence and immunopathogenesis.
Colomb F, et al. - Current HIV/AIDS reports
https://www.ncbi.nlm.nih.gov/pubmed/307074002018
N-glycosylation patterns of plasma proteins and immunoglobulin g in chronic obstructive pulmonary disease.
Pavic T, et al. - Journal of Translational Medicine
https://www.ncbi.nlm.nih.gov/pubmed/30463578Low galactosylation of igg associates with higher risk for future diagnosis of rheumatoid arthritis during 10 years of follow-up.
Gudelj I, et al. - Biochimica et Biophysica Acta
https://www.ncbi.nlm.nih.gov/pubmed/29572115The changes of immunoglobulin G n-glycosylation in blood lipids and dyslipidaemia.
Liu D, et al. - Journal of Translational Medicine
https://www.ncbi.nlm.nih.gov/pubmed/30157878Frontline Science: plasma and immunoglobulin g galactosylation associate with HIV persistence during antiretroviral therapy.
Vadrevu SK, et al. - Journal of Leukocyte Biology
https://www.ncbi.nlm.nih.gov/pubmed/29633346Deep molecular phenotypes link complex disorders and physiological insult to CPG methylation.
Zaghlool SB, et al. - Human Molecular Genetics
https://www.ncbi.nlm.nih.gov/pubmed/29325019Network inference from glycoproteomics data reveals new reactions in the igg glycosylation pathway.
Benedetti E, et al. - Nature Communications
https://www.ncbi.nlm.nih.gov/pubmed/29133956Promoter methylation of the mgat3 and bach2 genes correlates with the composition of the immunoglobulin g glycome in inflammatory bowel disease.
Klasic M, et al. - Clinical Epigenetics
https://www.ncbi.nlm.nih.gov/pubmed/29991969Glycosylation of immunoglobulin G associates with clinical features of inflammatory bowel diseases.
Simurina M, et al. - Gastroenterology
https://www.ncbi.nlm.nih.gov/pubmed/29309774The association between subclass-specific igg fc n-glycosylation profiles and hypertension in the Uygur, Kazak, Kirgiz, and Tajik populations.
Liu JN, et al. - Journal of Human Hypertension
https://www.ncbi.nlm.nih.gov/pubmed/29867134Glycosylation profile of immunoglobulin g is cross-sectionally associated with cardiovascular disease risk score and subclinical atherosclerosis in two independent cohorts.
Menni C, et al. - Circulation Research
https://www.ncbi.nlm.nih.gov/pubmed/29535164Genome-wide association study on immunoglobulin g glycosylation patterns.
Wahl A, et al. - Frontiers in Immunology
https://www.ncbi.nlm.nih.gov/pubmed/29535710The sweet spot for biologics: recent advances in characterization of biotherapeutic glycoproteins.
O'Flaherty R, et al. - Expert Review of Proteomics
https://www.ncbi.nlm.nih.gov/pubmed/29130774Igg glycan patterns are associated with type 2 diabetes in independent European populations.
Lemmers RFH, et al. - Biochimica et Biophysica Acta
https://www.ncbi.nlm.nih.gov/pubmed/28668296Igg glycosylation and DNA methylation are interconnected with smoking.
Wahl A, et al. - Biochimica et Biophysica Acta
https://www.ncbi.nlm.nih.gov/pubmed/29055820Increased central adiposity is associated with pro-inflammatory immunoglobulin g n-glycans.
Russell AC, et al. - Immunobiology
https://www.ncbi.nlm.nih.gov/pubmed/30446335Immunoglobulin G glycosylation in aging and diseases.
Gudelj I, et al. - Cell Immunol
https://www.ncbi.nlm.nih.gov/pubmed/301078932017
Ubiquitous importance of protein glycosylation.
Krištić J, et al. - Methods in Molecular Biology
https://www.ncbi.nlm.nih.gov/pubmed/27743354The n-glycosylation of immunoglobulin g as a novel biomarker of Parkinson's disease.
Russell AC, et al. - Glycobiology
https://www.ncbi.nlm.nih.gov/pubmed/28334832Connecting genetic risk to disease end points through the human blood plasma proteome.
Suhre K, et al. - Nature Communications
https://www.ncbi.nlm.nih.gov/pubmed/28240269Multivariate discovery and replication of five novel loci associated with immunoglobulin g n-glycosylation.
Shen X, et al. - Nature Communications
https://www.ncbi.nlm.nih.gov/pubmed/28878392Effects of statins on the immunoglobulin g glycome.
Keser T, et al. - Biochimica et Biophysica Acta
https://www.ncbi.nlm.nih.gov/pubmed/28263871Estrogens regulate glycosylation of igg in women and men.
Ercan A, et al. - JCI Insight, The Journal of Clinical Investigation
https://www.ncbi.nlm.nih.gov/pubmed/28239652Immunoglobulin g n-glycans as potential postgenomic biomarkers for hypertension in the Kazakh population.
Gao Q, et al. - Omics: a Journal of Integrative Biology
https://www.ncbi.nlm.nih.gov/pubmed/286924162016
The association between low back pain and composition of igg glycome.
Freidin MB, et al. - Scientific Reports
https://www.ncbi.nlm.nih.gov/pubmed/27229623Glycosylation of plasma igg in colorectal cancer prognosis.
Theodoratou E, et al. - Clinical Cancer Research
https://www.ncbi.nlm.nih.gov/pubmed/27302279IgG glycome in colorectal cancer.
Vuckovic F, et al. - Reports
https://www.ncbi.nlm.nih.gov/pubmed/26831718Precision medicine that transcends genomics: glycans as integrators of genes and environment.
Lauc G - Biochimica et Biophysica Acta
https://www.ncbi.nlm.nih.gov/pubmed/27155579The association between glycosylation of immunoglobulin g and hypertension: a multiple ethnic cross-sectional study.
Wang Y, et al. - Medicine
https://www.ncbi.nlm.nih.gov/pubmed/27124023Profiling igg n-glycans as potential biomarker of chronological and biological ages: a community-based study in a han Chinese population.
Yu X, et al. - Medicine
https://www.ncbi.nlm.nih.gov/pubmed/27428197Effects of allergic diseases and age on the composition of serum igg glycome in children.
Pezer M, et al. - Scientific Reports
https://www.ncbi.nlm.nih.gov/pubmed/27616597High-throughput analysis of immunoglobulin g glycosylation.
Trbojevic-Akmacic I, et al. - Expert Review of Proteomics
https://www.ncbi.nlm.nih.gov/pubmed/27043342Exploring the molecular basis of age-related disease comorbidities using a multi-omics graphical model.
Zierer J, et al. - Scientific Reports
https://www.ncbi.nlm.nih.gov/pubmed/27886242Glycosylation profile of igg in moderate kidney dysfunction.
Barrios C, et al. - JASN, Journal of the American Society of Nephrology
https://www.ncbi.nlm.nih.gov/pubmed/26185202Mechanisms of disease: the human n-glycome.
Lauc G, et al. - Biochimica et Biophysica Acta
https://www.ncbi.nlm.nih.gov/pubmed/265000992015
Integration of 'omics' data in aging research: from biomarkers to systems biology.
Zierer J, et al. - Aging Cell
https://www.ncbi.nlm.nih.gov/pubmed/26331998Estimation of human age using n-glycan profiles from bloodstains.
Gudelj I, et al. - International Journal of Legal Medicine
https://www.ncbi.nlm.nih.gov/pubmed/25787342Inflammatory bowel disease associates with proinflammatory potential of the immunoglobulin g glycome.
Trbojevic Akmacic I, et al. - Inflammatory Bowel Diseases
https://www.ncbi.nlm.nih.gov/pubmed/25895110Association of systemic lupus erythematosus with decreased immunosuppressive potential of the igg glycome.
Vuckovic F, et al. - Arthritis & Rheumatology
https://www.ncbi.nlm.nih.gov/pubmed/262006522014
Glycans - the third revolution in evolution.
Lauc G, et al. - Frontiers in Genetics
https://www.ncbi.nlm.nih.gov/pubmed/24904645Comparative performance of four methods for high-throughput glycosylation analysis of immunoglobulin g in genetic and epidemiological research.
Huffman JE, et al. - Molecular & Cellular Proteomics
https://www.ncbi.nlm.nih.gov/pubmed/24719452Glycans are a novel biomarker of chronological and biological ages.
Kristic J, et al. - The Journals of Gerontology, Series A
https://www.ncbi.nlm.nih.gov/pubmed/24325898Changes in igg and total plasma protein glycomes in acute systemic inflammation.
Novokmet M, et al. - Scientific Reports
https://www.ncbi.nlm.nih.gov/pubmed/24614541Epigenetic regulation of glycosylation is the quantum mechanics of biology.
Lauc G, et al. - Biochimica et Biophysica Acta
https://www.ncbi.nlm.nih.gov/pubmed/23999089The association between galactosylation of immunoglobulin g and body mass index.
Nikolac Perkovic M, et al. - Progress in Neuro-Psychopharmacology & Biological Psychiatry
https://www.ncbi.nlm.nih.gov/pubmed/24012618The role of glycosylation in ibd.
Theodoratou E, et al. - Nature Reviews Gastroenterology & Hepatology
https://www.ncbi.nlm.nih.gov/pubmed/249123892013
High-throughput igg fc n-glycosylation profiling by mass spectrometry of glycopeptides.
Pucic Bakovic M, et al. - Journal of Proteome Research
https://www.ncbi.nlm.nih.gov/pubmed/23298168Genomics and epigenomics of the human glycome.
Zoldos V, et al. - Glycoconjugate Journal
https://www.ncbi.nlm.nih.gov/pubmed/22648057Loci associated with n-glycosylation of human immunoglobulin g show pleiotropy with autoimmune diseases and haematological cancers.
Lauc G, et al. - PLOS Genetics
https://www.ncbi.nlm.nih.gov/pubmed/23382691Glycomics meets genomics, epigenomics and other high throughput omics for system biology studies.
Zoldos V, et al. - Current Opinion in Chemical Biology
https://www.ncbi.nlm.nih.gov/pubmed/23287290Glycosylation of immunoglobulin G: role of genetic and epigenetic influences.
Menni C, et al. - PLOS ONE
https://www.ncbi.nlm.nih.gov/pubmed/24324808Omics technologies and the study of human ageing.
Valdes AM, et al. - Nature Reviews Genetics
https://www.ncbi.nlm.nih.gov/pubmed/239383632012
Changes in plasma and igg n-glycome during childhood and adolescence.
Pucic M, et al. - Glycobiology
https://www.ncbi.nlm.nih.gov/pubmed/22727214The future of glycoscience.
Lauc G. - Biochimica et Biophysica Acta
https://www.ncbi.nlm.nih.gov/pubmed/22727214Alternative glycosylation modulates function of igg and other proteins - implications on evolution and disease.
Gornik O, et al. - Biochimica et Biophysica Acta
https://www.ncbi.nlm.nih.gov/pubmed/221830292011
Evolutional and clinical implications of the epigenetic regulation of protein glycosylation.
Horvat T, et al. - Clinical Epigenetics
https://www.ncbi.nlm.nih.gov/pubmed/22704355High throughput isolation and glycosylation analysis of igg-variability and heritability of the igg glycome in three isolated human populations.
Pucic M, et al. - Molecular & Cellular Proteomics
https://www.ncbi.nlm.nih.gov/pubmed/21653738High throughput plasma n-glycome profiling using multiplexed labelling and uplc with fluorescence detection.
Knezevic A, et al. - The Analyst
https://www.ncbi.nlm.nih.gov/pubmed/21956149Polymorphisms in b3gat1, slc9a9 and mgat5 are associated with variation within the human plasma n-glycome of 3533 european adults.
Huffman JE, et al. - Human Molecular Genetics
https://www.ncbi.nlm.nih.gov/pubmed/21908519Screening novel biomarkers for metabolic syndrome by profiling human plasma n-glycans in Chinese han and Croatian populations.
Lu JP, et al. - Journal of Proteome Research
https://www.ncbi.nlm.nih.gov/pubmed/219392252010
Effects of aging, body mass index, plasma lipid profiles, and smoking on human plasma n-glycans.
Knezevic A, et al. - Glycobiology
https://www.ncbi.nlm.nih.gov/pubmed/20356825Protein glycosylation-an evolutionary crossroad between genes and environment.
Lauc G, et al. - Molecular BioSystems
https://www.ncbi.nlm.nih.gov/pubmed/20957246Epigenetic regulation of protein glycosylation.
Zoldos V, et al. - Biomolecular Concepts
https://www.ncbi.nlm.nih.gov/pubmed/25962001Complex genetic regulation of protein glycosylation.
Lauc G, et al. - Molecular BioSystems
https://www.ncbi.nlm.nih.gov/pubmed/20094651Genomics meets glycomics-the first gwas study of human n-glycome identifies hnf1α as a master regulator of plasma protein fucosylation.
Lauc G, et al. - PLOS Genetics
https://www.ncbi.nlm.nih.gov/pubmed/212035002009
Stability of n-glycan profiles in human plasma.
Gornik O, et al. - Glycobiology
https://www.ncbi.nlm.nih.gov/pubmed/19726492Epigenetic regulation of glycosylation could be a mechanism used by complex organisms to compete with microbes on an evolutionary scale.
Lauc G, et al. - Medical Hypotheses
https://www.ncbi.nlm.nih.gov/pubmed/19560282Variability, heritability and environmental determinants of human plasma n-glycome.
Knezevic A, et al. - Journal of Proteome Research
https://www.ncbi.nlm.nih.gov/pubmed/190356622008
Glycosylation of serum proteins in inflammatory diseases.
Gornik O, et al. - Disease Markers
https://www.ncbi.nlm.nih.gov/pubmed/191269702006
Sweet secret of the multicellular life.
Lauc G. - Biochimica et Biophysica Acta
https://www.ncbi.nlm.nih.gov/pubmed/164310252004
Stress causes tissue-specific changes in the sialyltransferase activity.
Dabelic S, et al. - Zeitschrift fur Naturforschung C, A Journal of Biosciences
https://www.ncbi.nlm.nih.gov/pubmed/152419401999
Fucosylation of igg heavy chains is increased in rheumatoid arthritis.
Gornik I, et al. - Clinical Biochemistry
https://www.ncbi.nlm.nih.gov/pubmed/10638942Purification and maldi-ms characterization of stressin, a stress-associated glycoprotein.
Lauc G, et al. - Biological Chemistry
https://www.ncbi.nlm.nih.gov/pubmed/103556301998
Fucosylation and galactosylation of igg heavy chains differ between acute and remission phases of juvenile chronic arthritis.
Flögel M, et al. - Clinical Chemistry and Laboratory Medicine
https://www.ncbi.nlm.nih.gov/pubmed/95940461996
Changes of glycoprotein patterns in sera of humans under stress.
Barisic K, et al. - European Journal of Clinical Chemistry and Clinical Biochemistry
https://www.ncbi.nlm.nih.gov/pubmed/88336401991
Human brain gangliosides in development, aging and disease
Gordan Lauc et al. - Int. J. Dev. Biol.
http://www.ijdb.ehu.es/web/paper.php?doi=1814411
