Publications


GlycanAge is based on research performed on over 60,000 individuals. Here are the selected scientific publications in peer-reviewed journals describing the discoveries that lead to the GlycanAge test development and have enabled its continuous refinement.

Breaking the Glyco-Code of HIV Persistence and Immunopathogenesis. Colomb F, et al. Current HIV/AIDS reports, 2019.
The association between galactosylation of immunoglobulin G and body mass index. Nikolac Perkovic M, et al. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 2014.
Effects of statins on the immunoglobulin G glycome. Keser T, et al. Biochimica et Biophysica Acta, 2017.
Omics technologies and the study of human ageing. Valdes AM, et al. Nature Reviews Genetics, 2013.
Mechanisms of disease: The human N-glycome. Lauc G, et al. Biochimica et Biophysica Acta, 2016.
Variability, heritability and environmental determinants of human plasma N-glycome. Knezevic A, et al. Journal of Proteome Research, 2009.
Complex genetic regulation of protein glycosylation. Lauc G, et al. Molecular BioSystems, 2010.
Stability of N-glycan profiles in human plasma. Gornik O, et al. Glycobiology, 2009.
Glycosylation of plasma IgG in colorectal cancer prognosis. Theodoratou E, et al. Clinical Cancer Research, 2016.
Epigenetic regulation of protein glycosylation. Zoldos V, et al. Biomolecular Concepts, 2010.
Sweet secret of the multicellular life. Lauc G. Biochimica et Biophysica Acta, 2006.
The future of glycoscience. Lauc G. Biochimica et Biophysica Acta, 2012.
The association between low back pain and composition of IgG glycome. Freidin MB, et al. Scientific Reports, 2016.
The role of glycosylation in IBD. Theodoratou E, et al. Nature Reviews Gastroenterology & Hepatology, 2014.
High-throughput IgG Fc N-glycosylation profiling by mass spectrometry of glycopeptides. Pucic Bakovic M, et al. Journal of Proteome Research, 2013.
Genomics and epigenomics of the human glycome. Zoldos V, et al. Glycoconjugate Journal, 2013.
The changes of immunoglobulin G N-glycosylation in blood lipids and dyslipidaemia. Liu D, et al. Journal of Translational Medicine, 2018.
Epigenetic regulation of glycosylation is the quantum mechanics of biology. Lauc G, et al. Biochimica et Biophysica Acta, 2014.
Fucosylation of IgG heavy chains is increased in rheumatoid arthritis. Gornik I, et al. Clinical Biochemistry, 1999.
Glycans are a novel biomarker of chronological and biological ages. Kristic J, et al. The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, 2014.
Stress causes tissue-specific changes in the sialyltransferase activity. Dabelic S, et al. Zeitschrift fur Naturforschung C, A Journal of Biosciences, 2004.
IgG glycosylation and DNA methylation are interconnected with smoking. Wahl A, et al. Biochimica et Biophysica Acta, 2018.
Estimation of human age using N-glycan profiles from bloodstains. Gudelj I, et al. International Journal of Legal Medicine, 2015.
Glycans - the third revolution in evolution. Lauc G, et al. Frontiers in Genetics, 2014.
IgG glycome in colorectal cancer. Vuckovic F, et al. Reports, 2016.
Immunoglobulin G glycosylation in aging and diseases. Gudelj I, et al. Cell Immunol. 2018.
High-throughput analysis of immunoglobulin G glycosylation. Trbojevic-Akmacic I, et al. Expert Review of Proteomics, 2016.
Inflammatory bowel disease - glycomics perspective. Wang H, et al. Biochimica et Biophysica Acta, 2019.
Glycosylation of serum proteins in inflammatory diseases. Gornik O, et al. Disease Markers, 2008.
Changes of glycoprotein patterns in sera of humans under stress. Barisic K, et al. European Journal of Clinical Chemistry and Clinical Biochemistry: Journal of the Forum of European Clinical Chemistry Societies, 1996.
Glycosylation profile of IgG in moderate kidney dysfunction. Barrios C, et al. JASN, Journal of the American Society of Nephrology, 2016.
Translational glycobiology: from bench to bedside. Axford J, et al. Journal of Royal Society of Medicine, 2019.
Ubiquitous importance of protein glycosylation. Kristic J, et al. Methods in Molecular Biology, 2017.
Estrogens regulate glycosylation of IgG in women and men. Ercan A, et al. JJCI Insight,The Journal of Clinical Investigation, 2017