Elevate your scientific research with glycans

Download our comprehensive Glycan Research Matrix. We’ve complied a list of all research areas and how they correlate with specific disesase. Find out how Glycans correlate with your area of research and where they can offer additional insights.

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Most information dense biopolymers

Glycans are complex sugars, built from multiple simple sugars. Their unique and complex structure makes them the most information-dense biopolymers on earth.

Vital for cell-to-cell communication

Glycans bind to proteins and lipids, forming glycoproteins and glycolipids. The majority of our proteins are actually glycoproteins, and wouldn’t be functional without glycans.

Responsive to the environment

Glycans respond to interventions within a timeframe of 3-6 months and thus provide researchers with additional data points for their research.

Integrate multiple layers of information

Most genetic disease risks are defined at conception and can’t be changed. Glycans change during our lifetime in response to epigenetic and environmental factors.

Glycans hold key info for any research or trial

Research performed on over 200,000 people identified that glycans change 7-10 years before the disease is first diagnosed.

Glycans also respond to lifestyle interventions within a short timeframe, providing valuable insights.

If you’re interested in including glycans in your research, get in touch with us to see how we can collaborate.

Glycans are potent biomarkers for:

Aging

A catalogue of omics biological ageing clocks reveals substantial commonality and associations with disease risk (2022)

Immunoglobulin G glycans – Biomarkers and molecular effectors of aging (2022)

Heritability of the glycan clock of biological age (2022)

Disease detection and prediction

Immunoglobulin G N-Glycosylation Signatures in Incident Type 2 Diabetes and Cardiovascular Disease (2022)

IgG N-Glycosylation Is Altered in Coronary Artery Disease (2023)

Immunoglobulin G glycome com-position in transition from pre-menopause to postmenopause (2022)

Precision medicine and drug response

Total serum N‐glycans associate with response to immune checkpoint in-hibition therapy and survival in pati-ents with advanced melanoma (2023)

Altered IgG glycosylation at COVID-19 diagnosis predicts disease severity (2022)

Plasma N-glycome shows continuous deterioration as the diagnosis of insulin resistance approaches (2021)

Get Access to over 300 publications that show the link between Glycans and diseases like Cancer, Diabetes, Rheumatoid Arthritis, and more.

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Frequently Asked Questions

What’s the difference between glycation and glycosylation?

Sometimes, different types of sugars can be added to the same part of a protein. This is like how different words can be spelled with the same letters, or how people with different eye colors can have the same vision. This variation in sugar types is a bit like how genetic mutations can create different versions of genes. But with sugar structures, this variation is inherited from multiple genes, not just one.

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We’re pioneers in glycobiology

We collaborate with leading universities and process 85% of samples for high-throughput glycomic studies in the entire world! Our scientists regularly publish in world renowned Medical Journals.

We offer flexible research options

We offer multiple commercial protocols, for which we either need dried blood stains, frozen plasma or other tissue samples. As added value we can support you with ethics, study design, statistical analysis and research paper writing. We are also open to support you in applying for grants to finance your Glycan analysis.

	GlycanAge Dry blood spot	GlycanAge Frozen plasma	IgG glycome Dry blood spot	Plasma glycome Frozen plasma	Glycosylation analysis Frozen plasma, Mass spectrometry
Feasible for use in clinical trial
Intervention success evaluation
Basic disease association analysis					N/A
In depth disease association analysis					N/A
Novel biomarker discovery
For interventions shorter than 2 months
Site-specific glycosylation analysis
Individual GlycanAge Reports available
Population-level GlycanAge calculation available

Research options with frozen plasma also require basic laboratory equipment, storage on -20°C, and shipping on dry ice.

If you’re interested in including glycans in your research studies, get in touch with us to see how we can collaborate.

Get started today

Download our comprehensive research list or get in touch with us to see how we can work together.

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Or to discuss research options