GlycanAge publications

GlycanAge is based on research performed on over 200,000 people.

These findings identified that glycans change 7-10 years before the disease is first diagnosed. Glycans also respond to lifestyle interventions within a short timeframe, providing valuable insights.

If you’re interested in including glycans in your research, check out our Research page to see how we can collaborate.

You can see all of our publications in chronological order below.

2024

MMP3 single-nucleotide polymorphisms are associated with noncontact ACL injuries in competing high-level athletes

Šimunić-Briški N, et al. - Journal of Orthopaedic Research

https://pubmed.ncbi.nlm.nih.gov/37442641/

Influence of Desialylation on the Drug Binding Affinity of Human Alpha-1-Acid Glycoprotein Assessed by Microscale Thermophoresis

Šeba T, et al. - Pharmaceutics

https://www.mdpi.com/1999-4923/16/2/230
2023

The Association of the Polymorphisms in the FUT8-Related Locus with the Plasma Glycosylation in Post-Traumatic Stress Disorder

Tudor L, et al. - International Journal of Molecular Sciences

https://www.mdpi.com/1422-0067/24/6/5706
2022

Distinct Longitudinal Changes in Immunoglobulin G N-Glycosylation Associate with Therapy Response in Chronic Inflammatory Diseases

Jerko Štambuk et al - MDPI, International Journal of Molecular Sciences

https://www.mdpi.com/1422-0067/23/15/8473
2021

A Multi-Factorial Observational Study on Sequential Fecal Microbiota Transplant in Patients with Medically Refractory Clostridioides difficile Infection

Tanya M. Monaghan, et al. - Cells

https://www.mdpi.com/2073-4409/10/11/3234
2020
2019

Type 2 Diabetes Mellitus is Associated with the Immunoglobulin G N-Glycome through Putative Proinflammatory Mechanisms in an Australian Population.

Li X, et al. - Omics: a Journal of Integrative Biology

https://www.ncbi.nlm.nih.gov/pubmed/31526239

Next-Generation (Glycomic) Biomarkers for Cardiometabolic Health: A Community-Based Study of Immunoglobulin G N-Glycans in a Chinese Han Population.

Wang H, et al. - Omics: a Journal of Integrative Biology

https://www.ncbi.nlm.nih.gov/pubmed/31313980

Glycomics for Type 2 Diabetes Biomarker Discovery: Promise of Immunoglobulin G Subclass-Specific Fragment Crystallizable N-glycosylation in the Uyghur Population.

Liu J, et al. - Omics: a Journal of Integrative Biology

https://www.ncbi.nlm.nih.gov/pubmed/31393219

N-Glycan Analysis by Ultra-Performance Liquid Chromatography and Capillary Gel Electrophoresis with Fluorescent Labeling

Hanic M, et al. - Current protocols in protein science

https://www.ncbi.nlm.nih.gov/pubmed/31517449

Molecular Pathways Mediating Immunosuppression in Response to Prolonged Intensive Physical Training, Low-Energy Availability, and Intensive Weight Loss.

Sarin HV, et al. - Frontiers in Immunology

https://www.ncbi.nlm.nih.gov/pubmed/31134054

Glycomics for type 2 diabetes biomarker discovery: promise of immunoglobulin g subclass-specific fragment crystallizable n-glycosylation in the Uyghur population.

Liu J, et al. - Omics: a Journal of Integrative Biology

https://www.ncbi.nlm.nih.gov/pubmed/31393219

N-glycan analysis by ultra-performance liquid chromatography and capillary gel electrophoresis with fluorescent labelling.

Hanic M, et al. - Current protocols in protein science

https://www.ncbi.nlm.nih.gov/pubmed/31517449

Molecular pathways mediating immunosuppression in response to prolonged intensive physical training, low-energy availability, and intensive weight loss.

Sarin HV, et al. - Frontiers in Immunology

https://www.ncbi.nlm.nih.gov/pubmed/31134054

Type 2 diabetes mellitus is associated with the immunoglobulin g n-glycome through putative proinflammatory mechanisms in an Australian population.

Li X, et al. - Omics: a Journal of Integrative Biology

https://www.ncbi.nlm.nih.gov/pubmed/31526239

Next-generation (glycomic) biomarkers for cardiometabolic health: a community-based study of immunoglobulin g n-glycans in a Chinese Han population.

Wang H, et al. - Omics: a Journal of Integrative Biology

https://www.ncbi.nlm.nih.gov/pubmed/31313980
2018

The association between subclass-specific IgG Fc N-glycosylation profiles and hypertension in the Uygur, Kazak, Kirgiz, and Tajik populations.

Liu JN, et al. - Journal of Human Hypertension

https://www.ncbi.nlm.nih.gov/pubmed/29867134

Glycosylation profile of immunoglobulin G is cross-sectionally associated with cardiovascular disease risk score and subclinical atherosclerosis in two independent cohorts.

Menni C, et al. - Circulation Research

https://www.ncbi.nlm.nih.gov/pubmed/29535164

Low galactosylation of IgG associates with higher risk for future diagnosis of rheumatoid arthritis during 10 years of follow-up.

Gudelj I, et al. - Biochimica et Biophysica Acta

https://www.ncbi.nlm.nih.gov/pubmed/29572115

Promoter methylation of the MGAT3 and BACH2 genes correlates with the composition of the immunoglobulin G glycome in inflammatory bowel disease.

Klasic M, et al. - Clinical Epigenetics

https://www.ncbi.nlm.nih.gov/pubmed/29991969

Frontline Science: Plasma and immunoglobulin G galactosylation associate with HIV persistence during antiretroviral therapy.

Vadrevu SK, et al. - Journal of Leukocyte Biology

https://www.ncbi.nlm.nih.gov/pubmed/29633346

Low galactosylation of igg associates with higher risk for future diagnosis of rheumatoid arthritis during 10 years of follow-up.

Gudelj I, et al. - Biochimica et Biophysica Acta

https://www.ncbi.nlm.nih.gov/pubmed/29572115

Frontline Science: plasma and immunoglobulin g galactosylation associate with HIV persistence during antiretroviral therapy.

Vadrevu SK, et al. - Journal of Leukocyte Biology

https://www.ncbi.nlm.nih.gov/pubmed/29633346

Promoter methylation of the mgat3 and bach2 genes correlates with the composition of the immunoglobulin g glycome in inflammatory bowel disease.

Klasic M, et al. - Clinical Epigenetics

https://www.ncbi.nlm.nih.gov/pubmed/29991969

The association between subclass-specific igg fc n-glycosylation profiles and hypertension in the Uygur, Kazak, Kirgiz, and Tajik populations.

Liu JN, et al. - Journal of Human Hypertension

https://www.ncbi.nlm.nih.gov/pubmed/29867134

Glycosylation profile of immunoglobulin g is cross-sectionally associated with cardiovascular disease risk score and subclinical atherosclerosis in two independent cohorts.

Menni C, et al. - Circulation Research

https://www.ncbi.nlm.nih.gov/pubmed/29535164
2017
2016
2015
2014

Comparative performance of four methods for high-throughput glycosylation analysis of immunoglobulin G in genetic and epidemiological research.

Huffman JE, et al. - Molecular & Cellular Proteomics

https://www.ncbi.nlm.nih.gov/pubmed/24719452

Comparative performance of four methods for high-throughput glycosylation analysis of immunoglobulin g in genetic and epidemiological research.

Huffman JE, et al. - Molecular & Cellular Proteomics

https://www.ncbi.nlm.nih.gov/pubmed/24719452
2013
2012
2011

Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults.

Huffman JE, et al. - Human Molecular Genetics

https://www.ncbi.nlm.nih.gov/pubmed/21908519

High throughput isolation and glycosylation analysis of IgG-variability and heritability of the IgG glycome in three isolated human populations.

Pucic M, et al. - Molecular & Cellular Proteomics

https://www.ncbi.nlm.nih.gov/pubmed/21653738

High throughput isolation and glycosylation analysis of igg-variability and heritability of the igg glycome in three isolated human populations.

Pucic M, et al. - Molecular & Cellular Proteomics

https://www.ncbi.nlm.nih.gov/pubmed/21653738

Polymorphisms in b3gat1, slc9a9 and mgat5 are associated with variation within the human plasma n-glycome of 3533 european adults.

Huffman JE, et al. - Human Molecular Genetics

https://www.ncbi.nlm.nih.gov/pubmed/21908519
2010
2009
2008
2006
2004
1999
1998

Fucosylation and galactosylation of IgG heavy chains differ between acute and remission phases of juvenile chronic arthritis.

Flögel M, et al. - Clinical Chemistry and Laboratory Medicine

https://www.ncbi.nlm.nih.gov/pubmed/9594046

Fucosylation and galactosylation of igg heavy chains differ between acute and remission phases of juvenile chronic arthritis.

Flögel M, et al. - Clinical Chemistry and Laboratory Medicine

https://www.ncbi.nlm.nih.gov/pubmed/9594046
1996

Changes of glycoprotein patterns in sera of humans under stress.

Barisic K, et al. - European Journal of Clinical Chemistry and Clinical Biochemistry: Journal of the Forum of European Clinical Chemistry Societies

https://www.ncbi.nlm.nih.gov/pubmed/8833640
1991