GlycanAge Blog: Glycoscience
Learn about the science of glycans and their impact on health, aging, and disease. Explore groundbreaking research and medical advancements!


From Biomarker to Mortality Signal: How 20,000 Glycomes Are Reshaping Our Understanding of Aging and Disease
Standard clinical diagnostics are largely designed to identify pathology after significant physiological decline has already occurred. Blood glucose elevations indicate diabetes only after pancreatic function is compromised. LDL cholesterol marks cardiovascular risk after arterial changes have begun. C-reactive protei…
May 28, 2026
10 minutes

O-linked Glycosylation Explained
The blueprint for how proteins are formed is encoded in our DNA, but that’s only part of the story. Once a protein is built, it can undergo further modifications through the attachment of various molecules, altering its structure and function. These changes, collectively known as post-translational modifications, play…
August 27, 2024
10 minutes

Glycosylation: Impact on Health and Disease
Glycans are essential for all life. These are long-chain sugars that are present on proteins, lipids (also known as fats) and nucleic acids, and which make these biomolecules functional. When we think of sugars, our first thought may be about the sugars from food we eat, such as glucose and sucrose.
April 29, 2024
15 minutes

Glycation: Impact on Health and Disease
The core structure of proteins is built out of amino acids and it is encoded in our DNA. After the proteins are built, they can be further modified in various ways. Some of these modifications are strictly regulated and are crucial for the protein’s function, whereas others are spontaneous and can disrupt its activity…
April 24, 2024
15 minutes

Decoding Chronic Inflammation: Your Health's Hidden Compass
Inflammation is a fundamental and complex biological response, serving as the body's natural defense mechanism against injury, infection, and various forms of damage. However, it's important to recognize that not all inflammation is beneficial for us. When the body encounters infection or tissue damage, immune cells a…
October 23, 2023
10 minutes

The Power of Spermidine for Longevity: A Deep Dive into Its Benefits
In the quest for longevity, one compound has been creating quite a buzz: spermidine. This naturally occurring polyamine, found in all living organisms, has been linked to numerous health benefits, including the potential to increase lifespan. But what exactly is spermidine, and how does it contribute to longevity? Thi…
August 11, 2023
15 minutes

Do NAD Supplements Work to Promote Longevity? An In-Depth Look
In the quest for longevity, science has uncovered a crucial player: nicotinamide adenine dinucleotide (NAD). This coenzyme, present in all living cells, is a key player in our body's energy metabolism and cellular repair mechanisms. But its role extends beyond these functions, with emerging research suggesting it has …
August 11, 2023
10 minutes

Glycation vs Glycosylation: Examining Two Crucial Biochemical Processes
Biochemistry, the study of chemical processes within living organisms, is a complex and fascinating field. Within this realm, two phenomena, glycation and glycosylation, stand out for their profound impact on our health and well-being. Despite their phonetic similarity, these two mechanisms are distinct in nature and …
August 11, 2023
10 minutes

Protein & Antibody Glycosylation in Vaccines
Vaccines are a modern tool that helps us fight a variety of diseases. Since people are vaccinated and protected, there are 2 to 3 million fewer deaths worldwide.
July 7, 2023
5 minutes

Mind Full of Glycans
We truly have a treat for you - a lecture taught by Thomas Klarić, a member of our team researching the human glycome project. The lecture is titled The Mind Full of Glycans - an insight into the importance of glycans for the neurobiological processes in our brain.
November 17, 2021
5 minutes

Catching the Dominos As They Fall: A Breakthrough in the World of Glycans Might Help Cure Liver Disease
Glycans are essential for the proper functioning of almost any living being, including humans. The scientific community agrees that glycans are crucial to life as we know it. Still, the knowledge we have on them so far is greatly lacking and can be majorly improved. This is why new methods are constantly being develop…
June 30, 2021
5 minutes

Women Age Twice as Fast During Perimenopause
Antibodies are one of the main weapons in our arsenal for the eternal war against pathogens. They are an elaborate tool that can specifically recognise any foreign structure in our body. After binging to a foreign object, antibodies have to activate proper molecular mechanisms to deal with this foreign, non-self, obje…
April 18, 2021
5 minutes