Biological age and longevity blog: glycans, inflammation, and healthy aging · Page 23

The Sars-Cov-2 Spike Protein Is Densely Glycosylated

The spike protein is a trimeric protein on the surface of the SARS-CoV-2. This protein gives the whole viral family a crown-like appearance by forming spikes on their surface, hence their name – corona (Latin for crown). The spike protein mediates receptor recognition and membrane fusion during host cell infection. Du…

Published:
March 26, 2020 Reading time:
5 minutes

Glycans in Nanotechnology

Nanotechnology is technology, science and engineering conducted at the nanoscale, which is about 1 to 100 nanometers, to create, manipulate, and characterize structures on those scales. As it is shown, glycans are applicable biomarkers for medical diagnostic. It is known that material properties are changed on nanosca…

Published:
March 26, 2020 Reading time:
5 minutes

Have Glycans Finally Found a Place in Medicine?

Complex sugar molecules called glycans are an essential component to life as we know it since they are estimated to be the most abundant class of organic molecules on Earth. They are present in all domains of life, taking different shapes and sizes – from a single monosaccharide to the complex polysaccharides containi…

Published:
March 26, 2020 Reading time:
5 minutes

Intestinal Microbiota and Glycosylation

The human colon is extensively colonized with bacteria, fungi, and viruses. This colony of commensal, symbiotic and pathogenic microorganisms remains stable throughout the years but can change in some diseases (e.g., inflammatory bowel disease, HIV infection) and as a result of different environmental factors (e.g., d…

Published:
March 25, 2020 Reading time:
5 minutes

Glycosylation in Neurodegeneration

Since our world is rapidly ageing, neurodegenerative diseases, affecting mostly the elderly population, represent one of the most common causes of death. They are associated with a wide range of rather unpleasant symptoms, such as memory loss, mood changes, tremors, hallucinations, psychosis, depression and many more.…

Published:
March 25, 2020 Reading time:
5 minutes

Glycomic Diversity of Homogenous Cell Populations

Published:
March 24, 2020

A Targeted Approach to Determining the Human Glycome

Published:
March 24, 2020

Glycomes of Cancer and Autoimmune Diseases

Published:
March 24, 2020 Reading time:
5 minutes

Glycans as Biomarkers and Functional Effectors in Diabetes and Cardiovascular Diseases

Published:
March 24, 2020 Reading time:
5 minutes

The Human Glycome Project

Published:
March 24, 2020

Don’t Stress – Your Glycans Will Know

Glycans are complex carbohydrate molecules attached to many proteins and lipids. More than half of all our proteins are glycosylated, and the glycan part often significantly influences a protein's structure and function. Unlike other macromolecules such as RNA and proteins, the sequence of glycans is not predetermined…

Published:
March 24, 2020 Reading time:
5 minutes

Genes Regulating Variation of Protein N-Glycosylation in Human Populations

Published:
March 23, 2020