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Glycans as Drivers of a Disease Risk

The relative risk of many diseases increases with age. Individuals age at different rates, and while some might show a surprising level of health and fitness in their eight decades, others might be troubled by age-related diseases already in their late thirties. An increasing body of evidence suggests glycans play a role at establishing an individual’s risk of having poor health.

By Ph.D. Marina Martinic Kavur
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It’s Official – Stress Alters the Way Brain Proteins Are Glycosylated

A recently published study has shown for the first time that traumatic stress also leads to long-lasting changes in the glycosylation of brain proteins.

By Thomas Klarić
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The Role of Glycans and Water in the Seasonality of COVID-19

Can ranges in temperature and humidity decrease or increase COVID-19 severity and mortality? Read the article to find out more.

By Prof Gordan Lauc, PhD
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Effects of Estrogens on the GlycanAge Index of Biological Age

Could hormone replacement therapy have an impact on your biological age? Read more about a recent study, addressing this question by analysing GlycanAge in 36 healthy premenopausal women.

By Prof Gordan Lauc, PhD
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Can Glycans Predict the Loss of Kidney Function

Chronic kidney failure is one of the most common and debilitating complications of diabetes. Changes in glycosylation of immunoglobulin G (IgG) accompany biological agеing and regulates inflammation in diabetes – a process that participates in kidney function decline. A new study looks at the correlation between kidney function and IgG glycosylation.

By Ph.D. Marina Martinic Kavur
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Sialylation of Immunoglobulin E Is a Determinant of Allergic Pathogenicity

IgE glycan composition and specifically sialylation is established as an important regulator of allergic disease.

By Marija Pezer, PhD
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GlycanAge - the Best Biomarker of Biological Age

Over 10 years of research on over 100,000 people condensed in 13 min presentation of Prof Gordan Lauc at the Longevity Leaders Virtual 2020. Check this video for introduction about glycans and their role in ageing and disease.

By Prof Gordan Lauc, PhD
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Glycans Are Crucial for the Response to Sars Cov-2 Infection

Glycans play an important role in the course of SARS-CoV-2 infection and should not be overlooked when searching for ways to understand and control this new disease. Glycans might become a great biomarker tool to predict disease severity, response to therapy and recovery prognosis.

By Olga Zaitseva
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Glycans as Biomarkers of Ageing and Age-Related Diseases

A lecture by Professor Gordan Lauc, giving an overview of over a decade of research on more than 100 000 individuals which showed that IgG glycans are excellent biomarkers of ageing and age-related diseases.

By Prof Gordan Lauc, PhD
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