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CDG Disease: Congenital Disorders of Glycosylation

The glycosylation machinery inside the cell’s factories requires the coordinated action of hundreds of different enzymes working together in perfect harmony. If even one of these enzymes is not working properly, that can be a big problem.

By Mattia Vacchini and Thomas Klarić
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Measure, Normalise, Analyse

Glycans are complex sugar molecules that are present on the majority of proteins in the human body. As such, glycans have shown great potential as biomarkers of both biological and chronological ages, as well as various diseases, including cancer and autoimmune diseases.

By Azra Frkatović
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Glycosylation Profile of Sars-Cov-2 Spike Protein

Detailed glycan analysis and potential post-translational modifications of the SARS-CoV-2 spike protein is very important for the development of glycoprotein-based vaccine.

By Tea Petrovic
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Glycans in Drug Discovery - HIV Glycopeptide Antigens

Glycoproteins found at the surface of several viruses are called viral envelope glycoproteins and they are great targets for virus neutralization.

By Petra Tominac
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The Importance of IgG Glycosylation in Drug Development

IgG glycosylation is an important part of antibody-based drug production since it offers insights into the drug’s efficacy along with a more accurate prediction of the patient’s immune response to the drug.

By Ana Cindrić
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The Sars-Cov-2 Spike Protein Is Densely Glycosylated

The spike protein mediates receptor recognition and membrane fusion during host cell infection.

By Marija Pezer, PhD
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Have Glycans Finally Found a Place in Medicine?

Glycans, the complex sugar molecules, are an essential component of life.

By Tamara Pavic
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