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Sweet Beginnings: How Sugars Help to Build Your Brain

Did you know that there are special types of sugar chains, called glycans, that play a crucial role in brain formation? It's true! Read to find out more.

By Mattia Vacchini and Thomas Klarić
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Measure, Normalise, Analyse

Glycans are complex sugar molecules that are present on the majority of proteins in the human body. As such, glycans have shown great potential as biomarkers of both biological and chronological ages, as well as various diseases, including cancer and autoimmune diseases.

By Azra Frkatović
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Sweet Brain O'Mine: How Sugars Help You Think!

Next time you have breakfast, think about the sugars differently! Some of them might be bad in excess, but there is a whole world of sweet architectures interacting and communicating in your nerves, shaping the biochemical information that nurtures your thoughts.

By Mattia Vacchini and Thomas Klarić
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Glycosylation Profile of Sars-Cov-2 Spike Protein

Detailed glycan analysis and potential post-translational modifications of the SARS-CoV-2 spike protein is very important for the development of glycoprotein-based vaccine.

By Tea Petrovic
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Understanding Glycans in COVID-19 Drug Design

We need to intensify studies on the role of glycosylation and understand the importance of these complicated structures if we want to have success in the diagnosis, treatment, and prevention of the COVID-19.

By Mislav Novokmet, Maja Pučić Baković, Gordan Lauc
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Mucin 4 Glycoprotein Appears to Play an Important Role in Coronavirus Disease

Many surfaces of our body, including surface of the respiratory system (from the nose to the lung), eyes, ears, intestine and others, are covered by a layer called mucus. This mucus layer serves as the body's very first line of defence against pathogens (e.g. bacteria, viruses).

By Jasminka Krištić
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Glycans in Drug Discovery - HIV Glycopeptide Antigens

Glycoproteins found at the surface of several viruses are called viral envelope glycoproteins and they are great targets for virus neutralization.

By Petra Tominac
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Glycans as Biomarkers for Liver and Pancreatic Cancer

With cancer being one of the deadliest diseases on earth, the need for biomarkers that can determine the risk of developing it is extraordinary.

By Petra Tominac
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COVID19 Severity – Are Smokers at Risk?

We are all aware of the bad effect smoking has on our body and health but here is another reason while quitting is worthwhile.

By Jelena Šimunović
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The Importance of IgG Glycosylation in Drug Development

IgG glycosylation is an important part of antibody-based drug production since it offers insights into the drug’s efficacy along with a more accurate prediction of the patient’s immune response to the drug.

By Ana Cindrić
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Biomarkers of Biological Age as Predictors of COVID-19 Disease Severity

Early epidemiological studies suggest that age is the most important predictor of severity of COVID-19 disease course.

By Gordan Lauc, PhD and David Sinclair, PhD
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The Sars-Cov-2 Spike Protein Is Densely Glycosylated

The spike protein mediates receptor recognition and membrane fusion during host cell infection.

By Marija Pezer, PhD
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